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KMID : 1022820110020010005
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Journal of Multiple Sclerosis and Neuroimmunology
2011 Volume.2 No. 1 p.5 ~ p.10
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Neuromyelitis Optica Spectrum Disorders: Diagnostic Issues in Korea
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Min Ju-Hong
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Abstract
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Neuromyelitis optica (NMO) is a CNS demyelinating disorder, characterized by optic neuritis and acute myelitis. A specific autoantibody of NMO, NMO-IgG was recently detected, which resulted in the revision of the diagnostic criteria of NMO, proposed in 1999. The new diagnostic criteria emphasized the long cord lesion over 3 vertebral segments and the presence of NMO-IgG. In addition, with the positivity of NMO-IgG in longitudinal extensive myelitis, recurrent optic neuritis and autoimmune disorders, the spectrum of NMO-related disorders were broadened. The review for NMO spectrum disorders and NMO-IgG will provide a help to understand NMO, this rapidly disabling disease.
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KEYWORD
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Neuromyelitis optica, Myelitis, Optic neuritis
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